Attention to Drug Use After Kidney Transplantation!

Attention to Drug Use After Kidney Transplantation!
Attention to Drug Use After Kidney Transplantation!

Nephrology Specialist Assoc. Dr. Ali Minister said, “Patients who do not use their medications properly may be at risk for kidney rejection.”

Kidney transplantation is the best treatment option in terms of both life expectancy and quality of life for patients with end-stage renal disease, whose number reaches 60 thousand in our country today. Reminding that according to statistics, approximately 3500 kidney transplant operations are performed in our country every year, Nephrology Specialist Assoc. Dr. Ali Minister pointed out that patient compliance is very important in order to achieve the desired result after transplantation.


Underlining that kidney transplant treatment is a lifelong process, including pre- and post-operatively, Yeditepe University Koşuyolu Hospital Nephrology Specialist Assoc. Dr. Ali Balkan drew attention to the importance of the patient, who was at the center of the treatment in this process, to comply with the rules.


Assoc. Dr. "This figure is in the range of 90-95 percent for a 5-year period," said Ali Minister. Underlining that many factors, from the patient's condition to the experience of the nephrologist and surgical team, are effective in the success of kidney transplantation, Assoc. Dr. Ali Minister continued his words as follows: “For example, in the disease we define as focal segmental glomerulonephritis, which leads to very rapid kidney failure, the disease can recur even if the patient has a kidney transplant. Therefore, a definitive diagnosis of the underlying disease must be made. Accordingly, a strategy should be formed. In addition, the experience of the transplant team, who plans the transplantation from the planning to the surgery and the next treatment process, is also very important.”


Reminding that 5-10 percent of kidney transplant patients experience organ rejection for different reasons in the first year, Assoc. Dr. Ali Minister said, "As the immune system may reject the organ, factors such as the patient's use of medication or diet after transplantation may also affect this result. For this reason, one of the most important issues that patients should pay attention to after transplantation is regular physician check-ups and regular use of their medications. There is a risk of kidney rejection in patients who do not use their medications properly. We want to see our patients in the first year, every month, and then every 3 months in the following period. Medicines must be used for life.”


Reminding that most of the patients are careful about compliance with the drug, however, there may be some confusion as it is a long-term treatment, Assoc. Dr. Ali Minister said, “In this long-term treatment, sometimes the psychology of the patients may deteriorate and some fluctuations may occur. In this case, the first thing they do is stop taking their medication. Sometimes, patients may stop taking the drug by saying that I am completely healed. For this reason, it is very important for patients to undergo a general psychological evaluation for their compliance with treatment before transplantation. Because regardless of the reason, not using the drug can increase the risk of organ rejection. Since the effects of these drugs can sometimes last for a few days, of course, skipping a dose for 1-2 days does not pose such a great risk. But it also means that it will not give birth. They need to use their drugs very regularly. However, if longer-term drugs are neglected, it is a much greater risk in terms of organ rejection.”


Stating that another important point to be considered after kidney transplantation is the treatment of other diseases of the patient, Assoc. Dr. Ali Minister, "For example, if the blood sugar control of a patient who develops kidney failure due to diabetes cannot be achieved, the transplant kidney may also be affected. The same is true for patients with hypertension. Therefore, it is very important for the patient to get his life in order, eat regularly, pay attention to water consumption and remove salt from his life after kidney transplantation.

Explaining that the patient's weight control is also very important in the period after kidney transplantation, Assoc. Dr. Ali Minister said, “Obesity is an inflammatory process and it affects the vessels throughout the body and causes inflammation. Since there is a vascular bundle in the kidney, obesity can also cause deterioration of the kidney. Therefore, we do not want the patient to gain weight, and if he has gained weight, we make him lose weight.”


Reminding that there are around 60.000 patients undergoing dialysis in Turkey and that an average of 3500 transplants can be made from this pool per year, Yeditepe University Koşuyolu Hospital Nephrology Specialist Assoc. Dr. Ali Minister,'' It should not be forgotten that many problems can be solved by increasing the donation rates of Kadeverik. Compared to hemodialysis, kidney transplantation is a much more convenient solution method in terms of both medical, social and economic aspects. While only 10% of transplants in Turkey are made from cadavers, this rate is the opposite in the world. Therefore, it is necessary to increase organ donation in every layer of society.

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