Neoadjuvant Chemotherapy-Resistant Breast Cancer: Personalized Treatment Methods
Breast cancer is one of the most common types of cancer among women worldwide. This situation poses a significant problem in the field of health and requires continuous development of treatment methods. Especially neoadjuvant chemotherapy, is a frequently used method to shrink tumors before surgery. However, some patients may develop resistance to this treatment. In this article, we will discuss the treatment developed for breast cancer patients resistant to neoadjuvant chemotherapy. personalized treatment methods and we will provide comprehensive information about genetic research.
What is Neoadjuvant Chemotherapy?
Neoadjuvant chemotherapy is a treatment process applied to cancer patients before surgery. This process aims to reduce the size of tumors and increase the effect of surgery. However, each patient's response to treatment varies. Some patients have difficulty with the treatment process by resisting this treatment. Therefore, optimizing treatment methods is of great importance.
The Importance of Personalized Treatment Methods
Personalized treatment methods are developed based on the genetic and biological characteristics of patients. This approach makes the treatment process more effective. For resistant patients, identifying genetic biomarkers is a critical step to increase response to treatment. Genetic research, helps develop more effective treatment strategies by taking into account the individual characteristics of patients.
Genetic Biomarkers and Resistance Mechanisms
Resistance to neoadjuvant chemotherapy may be based on different genetic and biological factors in each patient. In order to understand this situation, genetic biomarkers need to be identified. Research provides important data for understanding the mechanisms of resistance. These data play an important role in personalizing treatment processes.
New Research and Developments
Genetic research conducted in collaboration with Istanbul University and Biruni University aims to develop new treatment methods for breast cancer patients resistant to neoadjuvant chemotherapy. In this project, genetic biomarkers will be identified, making the treatment processes of patients more effective. Such studies pave the way for revolutionary developments in cancer treatment.
Targeted Treatment Methods
Targeted treatment methods are one of the most important components of personalized treatment processes. These methods are designed in accordance with the patient's genetic structure and ensure that the treatment process is more successful. New treatment strategies to be developed for resistant patients may produce promising results. Developments in this area are considered an important turning point in cancer treatment.
Preventing Unnecessary Chemotherapy Applications
The research will help prevent unnecessary chemotherapy applications. Data obtained for resistant cases guides the treatment process. In this way, it is aimed to prevent patients from being exposed to unnecessary chemotherapy. Personalized treatment methods offer a great advantage in this respect.
As a result
In breast cancer treatment, it is of great importance to develop personalized treatment methods for patients who are resistant to neoadjuvant chemotherapy. Determination of genetic biomarkers ensures that treatment processes are more effective and successful. Such studies conducted by Istanbul University and Biruni University open the door to important developments in cancer treatment. Understanding the resistance mechanisms and applying targeted treatment methods will offer new hopes for patients.
