Founder of Istanbul Allergy Center, President of Allergy and Asthma Association Prof. Dr. Ahmet Akçay gave information. Can allergy sufferers get the Russian Vaccine Sputnik V vaccine? What is Sputnik V (Gam-COVID-Vac) Vaccine? How does Sputnik V Vaccine work? What is the difference of Sputnik V vaccine from other vector vaccines? What is the effectiveness rate of Sputnik V vaccine? What are the side effects of Sputnik V vaccine? Does Sputnik V vaccine have an allergy risk? Can those with allergic diseases get Sputnik V vaccine? Details of the questions are in our news.
Can allergy sufferers get the Russian Vaccine Sputnik V vaccine?
There are questions about the Sputnik V vaccine, one of the corona virus vaccines that will be introduced in our country in the near future. People with allergies in particular wonder whether they will develop an allergic reaction to this vaccine. Allergy and Asthma Association Prof. Dr. Ahmet Akçay explained the allergy risk and side effects of Sputnik V vaccine.
What is Sputnik V (Gam-COVID-Vac) Vaccine?
The Sputnik V vaccine, approved by the FDA after the completion of phase 3 studies, is a viral vector vaccine and is in the same group as the Johnson & Johnson and Oxford - AstraZeneca vaccine. The COVID-19 vaccine Sputnik V (Gam-COVID-Vac) is a vector vaccine based on adenovirus DNA in which the SARS-CoV-2 corona virus gene is integrated. It is administered intramuscularly separately with intervals of 21 days. The results showed that the vaccine was well tolerated and highly immunogenic in healthy participants.
How does Sputnik V Vaccine work?
Adenovirus is used as a virus vector, and a piece of DNA is inserted into this virus to synthesize the corona virus spike protein and injected into the body. This piece of DNA synthesizes the immune protein of the corona virus in our body, and immunity develops. This vaccine does not integrate into the person's DNA and does not cause disease. Therefore, it is a safe vaccine.
How is the Sputnik V vaccine different from other vector vaccines?
Two separate serotypes of adenovirus were used in the Sputnik V vaccine. One type of adenovirus was used as a vector in the Oxford-AstraZeneca vaccine and Johnson & Johnson vaccines.
What is the effectiveness rate of Sputnik V vaccine?
Sputnik V is a two-part adenovirus viral vector vaccine with a 91.6 percent efficacy rate. According to the latest information, the vaccine's effectiveness rate is 97.6 percent. It has been reported that the effectiveness of the Sputnik V vaccine against severe corona virus is 100 percent.
It has been reported to be an effective vaccine in terms of both antibody generation and cellular immunity. Adenoviral vector-administered antigens are reported to adequately maintain the body's immunity even after a single vaccination. It is reported that administration of two doses will develop much more effective and long-term immunity.
Is it more effective than other vector vaccines?
Two different types of adenovirus vectors have been used in the Sputnik V vaccine. As a result of the development of antibodies against adenovirus in the first dose, it appears that it is a much more effective vaccine since it eliminates the possibility of the decrease in the effectiveness of the second dose when the second dose is administered.
What are the side effects of Sputnik V vaccine?
Common side effects are influenza-like illness (15.2 percent) and reaction at the place of vaccination (5.4 percent). 94 percent of the side effects were mild, while 0,3 percent had serious side effects. There may be pain, swelling and redness at the vaccination site. Apart from this, headache, fatigue, muscle pain, chills, fever and nausea may occur. These side effects usually start within a day or two after the vaccine is given. Side effects can affect your daily activity ability, but they should go away within a few days. Serious side effects are extremely rare. As with any vaccine, it will be beneficial to wait 30 minutes in the hospital environment after this vaccine.
Does Sputnik V vaccine have an allergy risk?
There are no reported cases of allergy in the Phase 3 studies of the Sputnik V vaccine. Urticaria-like allergic reactions have been reported with other vector vaccines. Therefore, an allergic reaction such as urticaria may occur. Those who are allergic to one of the ingredients in the vaccine should not have this vaccine. Although the risk of allergies is low since this vaccine is a newly approved vaccine, it is important that you stay in the hospital environment for 30 minutes after vaccination and that precautions have been taken against the risk of allergies.
Can those with allergic diseases get Sputnik V vaccine?
Yes, he can. Those with allergic asthma, eczema, allergic rhinitis and other allergic diseases can get the Sputnik V, BioNTech and Chinese vaccine Coronavac vaccines. It will be beneficial for only those with allergic diseases to have their vaccinations in the hospital environment and to be under surveillance for 30 minutes after vaccination.
Can people with drug allergies get Sputnik V vaccine?
It is okay for those with drug allergies to have the Russian vaccine Sputnik V and Chinese vaccine Coronavac vaccine. If you are allergic to any of the components in the vaccine, the vaccine should not be given.
What should be done if the vaccine has a side effect?
If there is pain, swelling or redness in the area where the vaccine was applied; First of all, it will be appropriate to raise your arm to which the vaccine was administered. Instead of the vaccine, you can apply a towel soaked in cold water. Do not apply ice directly. You can use paracetamol pain relievers.
If tired; It will be helpful to rest and drink enough fluids.
Mild fever and chills; It is recommended that you rest, drink enough fluids, and take pain relievers containing paracetamol.
Headache; If a headache develops within a week after vaccination, it will be beneficial to take a pain reliever containing paracetamol.
Muscle and joint pain; If muscle and joint pain occurs within a week after the vaccination, it will be sufficient to rest, drink enough fluids and take paracetamol-containing painkillers.
Vomiting and diarrhea; If vomiting and diarrhea develop within a week after vaccination, it will be useful to take fluids and food orally. If there is insufficient fluid intake and weakness develops, the necessity of serum supplementation should be evaluated in the health institution.
As a result:
- Sputnik V vaccine side effects are similar to those of other COVID 19 vaccines.
- Sputnik V vaccine is an effective vaccine.
- The risk of allergies to Sputnik V vaccine is low.
- It is okay for those with asthma, allergic rhinitis, eczema, food allergy and drug allergies to have this vaccine.
- Waiting in the hospital environment for 30 minutes after vaccination will be beneficial in terms of possible allergic shock risk.
- It is very important to have equipment and personnel that can be intervened in case of allergic shock.
- It would be appropriate not to apply the second dose to those who have allergy symptoms after the first vaccine and these people should be evaluated by an allergist.